Announcement and Call for Papers 
 
                  The Evolution of Biomolecular Structures 
                and the Structure of Biomolecular Evolution 
  All biological macromolecules have an evolutionary origin that is 
manifested in essentially every aspect of their biological and 
physico-chemical properties. In order to 
understand these macromolecules, it is necessary to understand the 
relationship between these properties and the evolutionary pressures
that determined form and function.  
Information about the evolutionary history can be used to 
help predict the characteristics of these macromolecules.
Conversely, these macromolecules encode this evolutionary
heritage, and can provide insight into the 
process of molecular evolution. 
  Possible topics include:
 - Role of natural selection and self-organization in biomolecular evolution
 
- The relationship between sequence and structure evolution
 
- Structure-based evolutionary reconstruction
 
- Definition, significance, and evolution of protein cores, loops, and
    other conserved motifs
 
- Evolutionary interpretations of multiple sequence or structure alignments,
    including their use in biomolecular structure prediction
 
- The exon theory of protein structural organization
We welcome papers describing results from a wide range of possible
methodologies, including analyses of the databases of biomolecular 
sequences and structures, simple conceptual and computational 
evolutionary models, and experimental results.
People wishing to present posters without publishing a full paper may submit
an abstract.  Preregistration for the conference is required for the
inclusion of a paper in the conference proceedings. 
 Deadlines 
Paper submission deadline:                 July 27, 1995  
Notice to authors:                          September 11, 1995  
Final paper and preregistration deadline:   October 2, 1995  
 Track Chairs 
Richard A. Goldstein 
                     
Chemistry Department 
                                   
Biophysics Research Division 
                       
University of Michigan  
  
Ann Arbor, MI  48109-1055 USA  
  
+1 (313) 763-8013 
  
fax: +1 (313) 747-4865 
  
email: richardg@chem.lsa.umich.edu  
Russ B. Altman 
Section on Medical Informatics
Stanford University Medical Center, MSOB X-215 
Stanford, CA 94305-5479 USA 
+1 (415) 723-6979
fax: +1 (415) 725-7944 
email: altman@camis.stanford.edu